IL-17A modulator-2
IL-17A modulator-2 is a IL-17A modulator, extracted from patent WO2021239743+A1, example 27. IL-17A modulator-2 inhibits the biological action of IL-17A with a pIC50 of 8.3. IL-17A modulator-2 can be used for the research of diseases or disorders associated with modulation of IL-17A activity including diseases with an immune component or autoimmune pathol, cancer and neurodegenerative disorders[1].
Product Specifications
CAS Number
[2748749-47-3]
UNSPSC
12352005
Target
Interleukin Related
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/il-17a-modulator-2.html
Purity
98.44
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(C1=CC=NN1C)N[C@H](C(NC2=CC=C(C3=C(OC)C=[N+]([O-])C=C3OC)C=C2)=O)C(C4=CC=CC=C4)C5=CC=CC=C5
Molecular Formula
C33H31N5O5
Molecular Weight
577.63
References & Citations
[1]Barrie Phillip MARTIN, et al. Preparation of amino acid amides as IL-17A modulators. WO2021239743 A1.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
IL-17
Available Sizes
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