SEH inhibitor-17
SEH inhibitor-17 (compound 4f) is an oral active soluble epoxide hydrolase (sEH) inhibitor with the IC50 of 2.94 nM. sEH inhibitor-17 shows anti-inflammatory efficacy[1].
Product Specifications
CAS Number
2823295-37-8
UNSPSC
12352005
Target
Epoxide Hydrolase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/seh-inhibitor-17.html
Smiles
O=C(NS(=O)(C1=CC=C(C=C1)OC(F)(F)F)=O)NC23C[C@H](C4)C[C@H](C[C@H]4C3)C2
Molecular Formula
C18H21F3N2O4S
Molecular Weight
418.43
References & Citations
[1]Kundu B, et al. Evaluation of the Therapeutic Potential of Sulfonyl Urea Derivatives as Soluble Epoxide Hydrolase (sEH) Inhibitors. Molecules. 2024;29 (13) :3036.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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