Triphenylethylene
Triphenylethylene is an aromatic hydrocarbon that possesses weak estrogenic activity. Triphenylethylene antiestrogens relax duodenal intestinal muscle via a mechanism that involves inhibition of L-type Ca2+ channels but not activation of K+ channels[1].
Product Specifications
CAS Number
58-72-0
UNSPSC
12352005
Hazard Statement
H302, H319, H410
Target
Calcium Channel; Estrogen Receptor/ERR
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling; Vitamin D Related/Nuclear Receptor
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Endocrinology
Assay Protocol
https://www.medchemexpress.com/triphenylethylene.html
Purity
99.86
Smiles
C1=CC=C(C=C1)C=C(C2=CC=CC=C2)C3=CC=CC=C3
Molecular Formula
C20H16
Molecular Weight
256.34
Precautions
H302, H319, H410
References & Citations
[1]Díaz M. Triphenylethylene antiestrogen-induced acute relaxation of mouse duodenal muscle. Possible involvement of Ca2+ channels. Eur J Pharmacol. 2002 Jun 12;445 (3) :257-66.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
L-type calcium channel
Available Sizes
Frequently Asked Questions
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