Triphenylethylene

Triphenylethylene is an aromatic hydrocarbon that possesses weak estrogenic activity. Triphenylethylene antiestrogens relax duodenal intestinal muscle via a mechanism that involves inhibition of L-type Ca2+ channels but not activation of K+ channels[1].

Product Specifications

CAS Number

[58-72-0]

UNSPSC

12352005

Hazard Statement

H302, H319, H410

Target

Calcium Channel; Estrogen Receptor/ERR

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling; Vitamin D Related/Nuclear Receptor

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Endocrinology

Assay Protocol

https://www.medchemexpress.com/triphenylethylene.html

Purity

99.86

Smiles

C1=CC=C(C=C1)C=C(C2=CC=CC=C2)C3=CC=CC=C3

Molecular Formula

C20H16

Molecular Weight

256.34

Precautions

H302, H319, H410

References & Citations

[1]Díaz M. Triphenylethylene antiestrogen-induced acute relaxation of mouse duodenal muscle. Possible involvement of Ca2+ channels. Eur J Pharmacol. 2002 Jun 12;445 (3) :257-66.