CM026
CM026 is a selective aldehyde dehydrogenase 1A1 inhibitor with submicromolar inhibitory activity against aldehyde dehydrogenase 1A1. Its inhibitory mechanism is related to binding to the aldehyde binding pocket and utilizing a unique glycine residue. It can be used as a chemical tool to study the role of this enzyme in disease.
Product Specifications
CAS Number
851941-94-1
UNSPSC
12352005
Target
Others
Type
Reference compound
Related Pathways
Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/cm026.html
Smiles
O=C(N(C1=C(C2=O)N(C(CN3CCN(CC3)C(C4=COC=C4)=O)=N1)CCC(C)C)C)N2C
Molecular Formula
C22H30N6O4
Molecular Weight
442.51
References & Citations
[1]Design, synthesis of 1,3-dimethylpyrimidine-2,4-diones as potent and selective aldehyde dehydrogenase 1A1 (ALDH1A1) inhibitors with glucose consumption improving activity|[2]Characterization of two distinct structural classes of selective aldehyde dehydrogenase 1A1 inhibitors
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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