SDH-IN-14
SDH-IN-14 (Compound Z2) is an inhibitor of succinate dehydrogenase (SDH) . SDH-IN-14 has antifungal activity (EC50=2.7 μg/mL) against B.cinerea. SDH-IN-14 acts by disrupting the integrity of the cell wall and cell membrane[1].
Product Specifications
UNSPSC
12352005
Target
Fungal; Succinate Dehydrogenase
Type
Reference compound
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/sdh-in-14.html
Solubility
10 mM in DMSO
Smiles
O=C(NC1=NN=C(SCC(O)CN2C=CC3=C2C=CC=C3)S1)C4=CC=CC=C4C
Molecular Formula
C21H20N4O2S2
Molecular Weight
424.54
References & Citations
[1]He B, et al. Antifungal Activity of Novel Indole Derivatives Containing 1,3,4-Thiadiazole. J Agric Food Chem. 2024 May 8;72 (18) :10227-10235.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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