L-Hyoscyamine
L-Hyoscyamine (Daturine), a natural plant tropane alkaloid, is a potent and competitive muscarinic receptor (MR) antagonist. L-Hyoscyamine is a levo-isomer to Atropine (HY-B1205) [1][2].
Product Specifications
CAS Number
[101-31-5]
Product Name Alternative
Hyoscyamine
UNSPSC
12352005
Hazard Statement
H300, H330
Target
MAChR
Type
Natural Products
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/L-Hyoscyamine.html
Concentration
10mM
Purity
99.96
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CN1[C@@H]2C[C@@H](OC([C@@H](C3=CC=CC=C3)CO)=O)C[C@H]1CC2
Molecular Formula
C17H23NO3
Molecular Weight
289.38
Precautions
H300, H330
References & Citations
[1]Lars Göran Axelsson, et al. Regulatory role of 5-HT and muscarinic receptor antagonists on the migrating myoelectric complex in rats. Eur J Pharmacol. 2003 Apr 25;467 (1-3) :211-8.|[2]Harald John, et al. Application of an enantioselective LC-ESI MS/MS procedure to determine R- and S-hyoscyamine following intravenous atropine administration in swine. Drug Test Anal. Mar-Apr 2012;4 (3-4) :194-8.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
Launched
Available Sizes
Curated Selection
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