Monoolein

Monoolein is a biocompatible lipid molecule that can be used as a carrier for bone repair. Monoolein exhibits anti-inflammatory activity by inhibiting the immune response induced by LPS (HY-D1056) . It exerts its anti-inflammatory effects by reducing the production of immune response factors such as IL-12 p40, IL-6, and TNF-α, and inhibiting the generation of NO. Monoolein can be used in drug delivery and research in the field of inflammatory diseases [1][2].

Product Specifications

CAS Number

[111-03-5]

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

Endogenous Metabolite; Interleukin Related; NO Synthase; TNF Receptor

Type

Natural Products

Related Pathways

Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/monoolein.html

Purity

99.91

Solubility

Ethanol : 100 mg/mL (ultrasonic)

Smiles

CCCCCCCC/C=C\CCCCCCCC(OCC(O)CO)=O

Molecular Formula

C21H40O4

Molecular Weight

356.54

Precautions

H302, H315, H319, H335

References & Citations

[1]Ali I, et al. Monoolein, isolated from Ishige sinicola, inhibits lipopolysaccharide-induced inflammatory response by attenuating mitogen-activated protein kinase and NF-κB pathways. Food Sci Biotechnol. 2017 Apr 30;26 (2) :507-511.|[2]Issa JP, et al. Monoolein and chitosan gels as potential carriers of the rhBMP-2, using decortication surgical technique in Wistar rats as experimental model. Micron. 2008 Oct;39 (7) :952-9.