Chlorin e6 trimethyl ester

Chlorin e6 trimethyl ester, a methyl pheophorbide-a derivative, is a photosensitizer that can be used in photodynamic therapy (PDT) [1][2].

Product Specifications

CAS Number

[35038-32-5]

UNSPSC

12352005

Hazard Statement

H315, H319, H335

Target

Reactive Oxygen Species (ROS)

Type

Reference compound

Related Pathways

Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/chlorin-e6-trimethyl-ester.html

Purity

99.81

Solubility

DMSO : 10 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C(OC)C/C(C(NC(/C=C1C(CC)=C2C)=C3C)=C3C(OC)=O)=C(N=C(/C=C(C(C)=C/4C=C)\NC4=C/C2=N/1)[C@H]5C)\[C@H]5CCC(OC)=O

Molecular Formula

C37H42N4O6

Molecular Weight

638.75

Precautions

H315, H319, H335

References & Citations

[1]Pandey RK, et, al. Chlorin and porphyrin derivatives as potential photosensitizers in photodynamic therapy. Photochemistry and Photobiology. 1991. 53 (1) :65-72.|[2]Bauer D, et, al. Functionalization of chlorin e6 trimethylester towards potential amphiphilic photosensitizers for photodynamic therapy. Journal of Porphyrins and Phthalocyanines. 2019. 23 (3) : 243-250.