L-Aspartyl-L-phenylalanine
L-Aspartyl-L-phenylalanine is a metabolite of aspartame that can inhibit angiotensin converting enzyme (ACE) purified from rabbit lungs with a Ki of 11 μM[1].
Product Specifications
CAS Number
[13433-09-5]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Angiotensin-converting Enzyme (ACE) ; Drug Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/l-aspartyl-l-phenylalanine.html
Purity
98.0
Solubility
DMSO : 12.5 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
OC(C[C@H](N)C(N[C@H](C(O)=O)CC1=CC=CC=C1)=O)=O
Molecular Formula
C13H16N2O5
Molecular Weight
280.28
Precautions
H302, H315, H319, H335
References & Citations
[1]Grobelny D, et, al. A metabolite of aspartame inhibits angiotensin converting enzyme. Biochem Biophys Res Commun. 1985 Apr 30;128 (2) :960-4.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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