LDV-FITC
Product Specifications
UNSPSC Description
LDV-FITC, a fluorescent peptide, is a FITC-conjugated LDV peptide (HY-P2267). LDV-FITC binds to the α4β1 integrin with high affinity (Kd: 0.3 nM and 12 nM for binding to U937 cells in the presence and absence of Mn2+ respectively). LDV-FITC can be used to detect α4β1 integrin affinity[1][2].
Target Antigen
Integrin
Type
Peptides
Related Pathways
Cytoskeleton
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ldv-fitc.html
Purity
98.89
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C([C@@H](NC([C@@H](NC([C@@H](NC([C@@H]1CCCN1C([C@@H](NC([C@@H](NC([C@H](CC(C)C)NC(CC2=CC=C(NC(NC3=CC=CC=C3C)=O)C=C2)=O)=O)CC(O)=O)=O)C(C)C)=O)=O)C)=O)C)=O)CCCCNC(NC4=CC5=C(C=C4)C6(OC5=O)C7=C(C=C(C=C7)O)OC8=C6C=CC(O)=C8)=S)O
Molecular Weight
1368.51
References & Citations
[1]Hyduk SJ, et al. Phospholipase C, calcium, and calmodulin are critical for alpha4beta1 integrin affinity up-regulation and monocyte arrest triggered by chemoattractants. Blood. 2007 Jan 1;109(1):176-84.|[2]Chigaev A, et al. Real time analysis of the affinity regulation of alpha 4-integrin. The physiologically activated receptor is intermediate in affinity between resting and Mn(2+) or antibody activation. J Biol Chem. 2001 Dec 28;276(52):48670-8.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-P1188/LDV-FITC-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-P1188/LDV-FITC-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
1207610-07-8
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS2607732-01 48 Well
Canine Soluble Cluster of differentiation 21 (sCD21) ELISA Kit
Ask
View Details 
MBS2607732-02 96 Well
Canine Soluble Cluster of differentiation 21 (sCD21) ELISA Kit
Ask
View Details