Carcinine (dihydrochloride)
Carcinine (β-Alanylhistamine) dihydrochloride is the dihydrochloride salt of Carcinine. Carcinine is a selective and orally active histamine H3 receptor antagonist with a Ki of 0.2939 μM. Carcinine can reduce histamine content. Carcinine exhibits anti-oxidant activity and neuroprotective effects. Carcinine shows positive inotropic effect and can reduce blood sugar and blood lipid levels. Carcinine can be used for the researches of inflammation, neurological, cardiovascular and metabolic disease, such as retinal damage, seizure and diabetes[1][2][3][4][5].
Product Specifications
CAS Number
57022-38-5
Product Name Alternative
β-Alanylhistamine (dihydrochloride)
UNSPSC
12352005
Hazard Statement
H315, H318, H335
Target
Histamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease; Inflammation/Immunology; Neurological Disease; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/carcinine-dihydrochloride.html
Purity
99.39
Solubility
H2O : 175 mg/mL (ultrasonic)
Smiles
O=C(NCCC1=CN=CN1)CCN.[H]Cl.[H]Cl
Molecular Formula
C8H16Cl2N4O
Molecular Weight
255.14
Precautions
H315, H318, H335
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
H1 Receptor; H2 Receptor; H3 Receptor
Available Sizes
Frequently Asked Questions
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