SLC26A3-IN-3

SLC26A3-IN-3 (compound 4az) is a SLC26A3 inhibitor (IC50: 40 nM) . SLC26A3-IN-3 can be used for research of constipation, cystic fibrosis[1].

Product Specifications

CAS Number

[2369983-43-5]

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

GLUT

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/slc26a3-in-3.html

Solubility

10 mM in DMSO

Smiles

O=C(O)CC1=C(C)C2=CC=C(OCC3=CC=CC(I)=C3)C(C)=C2OC1=O

Molecular Formula

C20H17IO5

Molecular Weight

464.25

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362-P403+P233-P405-P501

References & Citations

[1]Lee S, et al. 4,8-Dimethylcoumarin Inhibitors of Intestinal Anion Exchanger slc26a3 (Downregulated in Adenoma) for Anti-Absorptive Therapy of Constipation. J Med Chem. 2019 Sep 12;62 (17) :8330-8337.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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