Isobutyl-deoxynyboquinone
Selected Variant
HY-125027-01
Size: 5 mg
Isobutyl-deoxynyboquinone (IB-DNQ) is a selective substrate for NAD (P) H:quinone oxidoreductase (NQO1) . Isobutyl-deoxynyboquinone can be used for the research of anticancer[1].
Product Specifications
CAS Number
1430798-22-3
Product Name Alternative
IB-DNQ
UNSPSC
12352005
Target
Quinone Reductase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/isobutyl-deoxynyboquinone.html
Purity
99.70
Solubility
DMSO : 10 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C1N(CC(C)C)C2=C(C(C(C(C)=CC(N3)=O)=C3C2=O)=O)C(C)=C1
Molecular Formula
C18H18N2O4
Molecular Weight
326.35
References & Citations
[1] Lundberg AP, et al. Pharmacokinetics and derivation of an anticancer dosing regimen for the novel anti-cancer agent isobutyl-deoxynyboquinone (IB-DNQ), a NQO1 bioactivatable molecule, in the domestic felid species. Invest New Drugs. 2017;35 (2) :134-144.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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