Isobutyl-deoxynyboquinone

Isobutyl-deoxynyboquinone (IB-DNQ) is a selective substrate for NAD (P) H:quinone oxidoreductase (NQO1) . Isobutyl-deoxynyboquinone can be used for the research of anticancer[1].

Product Specifications

CAS Number

[1430798-22-3]

Product Name Alternative

IB-DNQ

UNSPSC

12352005

Target

Quinone Reductase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/isobutyl-deoxynyboquinone.html

Purity

99.70

Solubility

DMSO : 10 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C1N(CC(C)C)C2=C(C(C(C(C)=CC(N3)=O)=C3C2=O)=O)C(C)=C1

Molecular Formula

C18H18N2O4

Molecular Weight

326.35

References & Citations

[1] Lundberg AP, et al. Pharmacokinetics and derivation of an anticancer dosing regimen for the novel anti-cancer agent isobutyl-deoxynyboquinone (IB-DNQ), a NQO1 bioactivatable molecule, in the domestic felid species. Invest New Drugs. 2017;35 (2) :134-144.