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Fiztasovimab

Product Specifications

UNSPSC Description

Fiztasovimab (NPC-21; EV2038) is a fully human IgG1λ mAb against human cytomegalovirus (hCMV). Fiztasovimab acts neutralizing activity by binding to the antigenic domain 1 of glycoprotein B on hCMV envelope. Fiztasovimab inhibits cell-to-cell transmission of hCMV[1].

Target Antigen

CMV

Type

Inhibitory Antibodies

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/fiztasovimab.html

Purity

96.49

Solubility

10 mM in DMSO

Smiles

[Fiztasovimab]

References & Citations

[1]Furihata K, et al. Pharmacokinetics, Safety, and Tolerability of NPC-21, an Anti-Cytomegalovirus Monoclonal Antibody, in Healthy Japanese and White Adult Men: A Randomized, Placebo-Controlled, First-in-Human Phase 1 Study. Clin Pharmacol Drug Dev. 2022 Jun;11(6):707-716.

Shipping Conditions

Dry Ice

Storage Conditions

Store at -80°C for 2 years

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-P99621/Fiztasovimab-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-P99621/Fiztasovimab-SDS-MedChemExpress.pdf

Clinical Information

Phase 2

CAS Number

2467411-25-0

Available Sizes

Curated Selection

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