Myristolated PKCz Pseudosubstrate ZIP Scrambled

<strong>Myristolated PKCz Pseudosubstrate ZIP Scrambled </strong>_x000D_ <strong>Catalog number:</strong> B2011210_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 1 mg_x000D_ <strong>Molecular Weight or Concentration:</strong> 1928.5_x000D_ <strong>Supplied as:</strong> Lyophilized_x000D_ <strong>Applications:</strong> molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20 °C_x000D_ <strong>Keywords:</strong> Myristolated PKC Zeta Pseudosubstrate ZIP Scrambled_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Lim S, Choi JW, Kim HS, Kim YH, Yea K, Heo K, Kim JH, Kim SH, Song M, Kim JI, Ryu SH, Suh PG. A myristoylated pseudosubstrate peptide of PKC-zeta induces degranulation in HMC-1 cells independently of PKC-zeta activity Life Sci. 2008 Mar 26;82(13-14):733-40._x000D_ 2: Lee-Rivera I, López E, Alvarez-Arce A, López-Colomé AM. The PKC-ζ pseudosubstrate peptide induces glutamate release from retinal pigment epithelium cells through kinase- independent activation of Best1 Life Sci. 2021 Jan 15;265:118860._x000D_ 3: Eichholtz T, de Bont DB, de Widt J, Liskamp RM, Ploegh HL. A myristoylated pseudosubstrate peptide, a novel protein kinase C inhibitor J Biol Chem. 1993 Jan 25;268(3):1982-6._x000D_ 4: Verhoeven AJ, Leusen JH, Kessels GC, Hilarius PM, de Bont DB, Liskamp RM. Inhibition of neutrophil NADPH oxidase assembly by a myristoylated pseudosubstrate of protein kinase C J Biol Chem. 1993 Sep 5;268(25):18593-8._x000D_ 5: Cao YJ, Li JY, Wang PX, Lin ZR, Yu WJ, Zhang JG, Lu J, Liu PQ. PKC-ζ Aggravates Doxorubicin-Induced Cardiotoxicity by Inhibiting Wnt/β-Catenin Signaling Front Pharmacol. 2022 Feb 14;13:798436._x000D_ 6: Harris TE, Persaud SJ, Saermark T, Jones PM. A myristoylated pseudosubstrate peptide inhibitor of protein kinase C: effects on glucose- and carbachol-induced insulin secretion Mol Cell Endocrinol. 1996 Aug 9;121(2):133-41._x000D_ 7: Harishchandran A, Nagaraj R. Interaction of a pseudosubstrate peptide of protein kinase C and its myristoylated form with lipid vesicles: only the myristoylated form translocates into the lipid bilayer Biochim Biophys Acta. 2005 Jul 30;1713(2):73-82._x000D_ 8: Bergman PJ, Gravitt KR, Ward NE, Beltran P, Gupta KP, O'Brian CA. Potent induction of human colon cancer cell uptake of chemotherapeutic drugs by N-myristoylated protein kinase C-alpha (PKC-alpha) pseudosubstrate peptides through a P-glycoprotein-independent mechanism Invest New Drugs. 1997;15(4):311-8._x000D_ 9: Gupta KP, Ward NE, Gravitt KR, Bergman PJ, O'Brian CA. Partial reversal of multidrug resistance in human breast cancer cells by an N-myristoylated protein kinase C-alpha pseudosubstrate peptide J Biol Chem. 1996 Jan 26;271(4):2102-11._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/9272125">10: Bergman PJ, Gravitt KR, O'Brian CA. An N-myristoylated protein kinase C-alpha pseudosubstrate peptide that functions as a multidrug resistance reversal agent in human breast cancer cells is not a P-glycoprotein substrate Cancer Chemother Pharmacol. 1997;40(5):453-6. </a>_x000D_ _x000D_ <strong>Products Related to Myristolated PKCz Pseudosubstrate ZIP Scrambled can be found at</strong> <a href="https://moleculardepot.com/product-category/Substrates/"> Substrates</a>