CDK7-IN-29
CDK7-IN-29 (compound 20) is an inhibitor of CDK7 with an IC50 value of 1.4 nM. CDK7-IN-29 has oral activity and good pharmacokinetic (PK) properties[1].
Product Specifications
CAS Number
3024545-83-0
UNSPSC
12352005
Target
CDK
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cdk7-in-29.html
Smiles
O=C1C2(CC2)C3=CC=C(C(C4=N5)=CSC4=CN=C5N[C@H]6CCCNC6)C=C3N1
Molecular Formula
C21H21N5OS
Molecular Weight
391.49
References & Citations
[1]Hongjin Zhang, et al. Design, synthesis and evaluation of thieno[3,2-d]pyrimidine derivatives as novel potent CDK7 inhibitors. Bioorg Chem. 2024 Jul:148:107456.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CDK7
Frequently Asked Questions
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