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Maslinic acid

Maslinic acid can inhibit the DNA-binding activity of NF-κB p65 and abolish the phosphorylation of IκB-α, which is required for p65 activation.

Product Specifications

CAS Number

[4373-41-5]

Product Name Alternative

Crategolic acid; 2α-Hydroxyoleanolic acid

UNSPSC

12352211

Target

Bacterial; Endogenous Metabolite; HIV; NF-κB

Type

Natural Products

Related Pathways

Anti-infection; Metabolic Enzyme/Protease; NF-κB

Applications

COVID-19-anti-virus

Field of Research

Inflammation/Immunology; Cancer

Assay Protocol

https://www.medchemexpress.com/Maslinic-acid.html

Purity

99.87

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

C[C@]([C@@]1([H])[C@]2(C[C@@H](O)[C@@H]3O)C)(CC[C@@]2([H])C3(C)C)[C@@](C4=CC1)(CC[C@]5(C(O)=O)[C@@]4([H])CC(C)(C)CC5)C

Molecular Formula

C30H48O4

Molecular Weight

472.70

References & Citations

[1]Fukumitsu S, et al. Anti-inflammatory and anti-arthritic effects of pentacyclic triterpenoids maslinic acid through NF-κB inactivation. Mol Nutr Food Res. 2016 Feb;60 (2) :399-409.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Natural Products

Clinical Information

No Development Reported

Isoform

RelA/p65

Available Sizes

Curated Selection

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