AMC Arachidonoyl Amide
AMC arachidonoyl amide (AMC-AA) is one of several fatty acid amides which can be used to measure fatty acid amide hydrolase (FAAH) activity.1 FAAH is a relatively unselective enzyme in that it accepts a variety of amide head groups other than the ethanolamine of its nominal endogenous substrate anandamide.2 Exposure of AMC-AA to FAAH activity results in the release of the fluorescent aminomethyl coumarin that absorbs at 360 nm and emits at 465 nm. This allows the fast and convenient measurement of FAAH activity using a simple cuvette or microplate fluorometer.
Product Specifications
CAS Number
[862913-13-1]
Product Name Alternative
AMC-AA; 7-Amino-4-methyl coumarin-arachidonamide
UNSPSC
12352005
Target
Endogenous Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/amc-arachidonoyl-amide.html
Purity
99.50
Smiles
CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(NC1=CC=C(C(O2)=C1)C(C)=CC2=O)=O
Molecular Formula
C30H39NO3
Molecular Weight
461.64
References & Citations
[1]Cravatt, et al. Molecular characterization of an enzyme that degrades neuromodulatory fatty-acid amides. Nature 384, 83-87 (1996) .
Shipping Conditions
Dry Ice
Storage Conditions
-80°C
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
