MKC9989
MKC9989 is a Hydroxy aryl aldehydes (HAA) inhibitor and also inhibits IRE1α with an IC50 of 0.23 to 44 μM.
Product Specifications
CAS Number
[1338934-20-5]
UNSPSC
12352005
Target
IRE1
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/MKC9989.html
Purity
98.33
Solubility
DMSO : ≥ 50 mg/mL
Smiles
O=CC1=C(O2)C(C(C)=C(CCOCCOC)C2=O)=CC(OC)=C1O
Molecular Formula
C17H20O7
Molecular Weight
336.34
References & Citations
[1]Sanches M, et al. Structure and mechanism of action of the hydroxy-aryl-aldehyde class of IRE1 endoribonuclease inhibitors. Nat Commun. 2014 Aug 28;5:4202.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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