4- (Trifluoromethyl) umbelliferone

4- (Trifluoromethyl) umbelliferone is fluorescent probe substrate for rat hepatic cytochrome P450 enzymes[1].

Product Specifications

CAS Number

[575-03-1]

UNSPSC

12171500

Hazard Statement

H300, H315, H319, H335

Target

Cytochrome P450

Type

Dye Reagents

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/4-trifluoromethyl-umbelliferone.html

Purity

99.83

Solubility

DMSO : ≥ 100 mg/mL

Smiles

O=C1C=C(C(F)(F)F)C2=CC=C(O)C=C2O1

Molecular Formula

C10H5F3O3

Molecular Weight

230.14

Precautions

H300, H315, H319, H335

References & Citations

[1]Renwick AB, et, al. Evaluation of 7-benzyloxy-4-trifluoromethylcoumarin, some other 7-hydroxy-4-trifluoromethylcoumarin derivatives and 7-benzyloxyquinoline as fluorescent substrates for rat hepatic cytochrome P450 enzymes. Xenobiotica. 2001 Dec;31 (12) :861-78.