Human CD7 Protein

<strong>Human CD7 Protein</strong>_x000D_ <strong>Catalog number:</strong> B2011887_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 100 µg_x000D_ <strong>Molecular Weight or Concentration:</strong> 1 mg/mL_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20 °C_x000D_ <strong>Keywords:</strong> T-cell antigen CD7 protein, GP40 protein, LEU-9 protein, Tp40 protein, TP41 protein, CD 7 protein, CD-7 protein_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Gomes-Silva D, Srinivasan M, Sharma S, Lee CM, Wagner DL, Davis TH, Rouce RH, Bao G, Brenner MK, Mamonkin M. CD7-edited T cells expressing a CD7-specific CAR for the therapy of T-cell malignancies Blood. 2017 Jul 20;130(3):285-296._x000D_ 2: Lu P, Liu Y, Yang J, Zhang X, Yang X, Wang H, Wang L, Wang Q, Jin D, Li J, Huang X. Naturally selected CD7 CAR-T therapy without genetic manipulations for T-ALL/LBL: first-in-human phase 1 clinical trial Blood. 2022 Jul 28;140(4):321-334._x000D_ 3: Lyman SD, Escobar S, Rousseau AM, Armstrong A, Fanslow WC. Identification of CD7 as a cognate of the human K12 (SECTM1) protein J Biol Chem. 2000 Feb 4;275(5):3431-7._x000D_ 4: Trotman-Grant AC, Mohtashami M, De Sousa Casal J, Martinez EC, Lee D, Teichman S, Brauer PM, Han J, Anderson MK, Zúñiga-Pflücker JC. DL4-μbeads induce T cell lineage differentiation from stem cells in a stromal cell-free system Nat Commun. 2021 Aug 18;12(1):5023._x000D_ 5: Shukla S, Langley MA, Singh J, Edgar JM, Mohtashami M, Zúñiga-Pflücker JC, Zandstra PW. Progenitor T-cell differentiation from hematopoietic stem cells using Delta-like-4 and VCAM-1 Nat Methods. 2017 May;14(5):531-538._x000D_ 6: Zhang M, Chen D, Fu X, Meng H, Nan F, Sun Z, Yu H, Zhang L, Li L, Li X, Wang X, Wang M, You F, Li Z, Chang Y, Zhou Z, Yan J, Li J, Wu X, Wang Y, Wang Y, Xiang S, Chen Y, Pan G, Xu H, Zhang B, Yang L. Autologous Nanobody-Derived Fratricide-Resistant CD7-CAR T-cell Therapy for Patients with Relapsed and Refractory T-cell Acute Lymphoblastic Leukemia/Lymphoma Clin Cancer Res. 2022 Jul 1;28(13):2830-2843._x000D_ 7: Bremer E, Samplonius DF, Peipp M, van Genne L, Kroesen BJ, Fey GH, Gramatzki M, de Leij LF, Helfrich W. Target cell-restricted apoptosis induction of acute leukemic T cells by a recombinant tumor necrosis factor-related apoptosis-inducing ligand fusion protein with specificity for human CD7 Cancer Res. 2005 Apr 15;65(8):3380-8._x000D_ 8: Myers DE, Jun X, Clementson D, Donelson R, Sicheneder A, Hoffman N, Bell K, Sarquis M, Langlie MC, Turner N, Uckun FM. Large scale manufacturing of TXU(anti-CD7)-pokeweed antiviral protein (PAP) immunoconjugate for clinical trials Leuk Lymphoma. 1997 Oct;27(3-4):275-302._x000D_ 9: Uckun FM, Chelstrom LM, Tuel-Ahlgren L, Dibirdik I, Irvin JD, Langlie MC, Myers DE. TXU (anti-CD7)-pokeweed antiviral protein as a potent inhibitor of human immunodeficiency virus Antimicrob Agents Chemother. 1998 Feb;42(2):383-8._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/7544374">10: Schanberg LE, Lee DM, Fleenor DE, Ware RE, Patel DD, Haynes BF, Kaufman RE. Characterization of human CD7 transgenic mice J Immunol. 1995 Sep 1;155(5):2407-18.</a>_x000D_ _x000D_ <strong>Products Related to Human CD7 Protein can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>