Isodorsmanin A

Isodorsmanin A is an anti-inflammatory agent. Isodorsmanin A suppresses the production of inflammatory mediators and proinflammatory cytokines. Isodorsmanin A inhibits the phosphorylation of JNK, MAPK[1].

Product Specifications

CAS Number

[118266-99-2]

UNSPSC

12352005

Hazard Statement

H315-H319-H335

Target

JNK; p38 MAPK

Type

Natural Products

Related Pathways

MAPK/ERK Pathway

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/isodorsmanin-a.html

Solubility

10 mM in DMSO

Smiles

OC(C=C1)=CC=C1/C=C/C(C2=C3C(CCC(C)(C)O3)=C(O)C=C2)=O

Molecular Formula

C20H20O4

Molecular Weight

324.37

Precautions

P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

References & Citations

[1]Chung YC, et al. Isodorsmanin A Prevents Inflammatory Response in LPS-Stimulated Macrophages by Inhibiting the JNK and NF-κB Signaling Pathways. Curr Issues Mol Biol. 2023 Feb 13;45 (2) :1601-1612.