Human CD40LG Protein

<strong>Human CD40LG Protein</strong>_x000D_ <strong>Catalog number:</strong> B2011881_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 100 µg_x000D_ <strong>Molecular Weight or Concentration:</strong> 0.5 mg/mL_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20 °C_x000D_ <strong>Keywords:</strong> CD40 ligand protein, CD-40LG BLGocking Peptide, CD 40LG BLGocking Peptide, gp39; hCD40L protein, TRAP protein, CD40LG, CD 40LG, T-BAM protein, HIGM1 protein, CD-40LG, IGM protein, CD154 protein, TNFSF5 protein, CD40L protein, IMD3 protein_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Karnell JL, Rieder SA, Ettinger R, Kolbeck R. Targeting the CD40-CD40L pathway in autoimmune diseases: Humoral immunity and beyond Adv Drug Deliv Rev. 2019 Feb 15;141:92-103._x000D_ 2: Aloui C, Prigent A, Tariket S, Sut C, Fagan J, Cognasse F, Chakroun T, Garraud O, Laradi S. Levels of human platelet-derived soluble CD40 ligand depend on haplotypes of CD40LG-CD40-ITGA2 Sci Rep. 2016 Apr 20;6:24715._x000D_ 3: Kuhn NF, Purdon TJ, van Leeuwen DG, Lopez AV, Curran KJ, Daniyan AF, Brentjens RJ. CD40 Ligand-Modified Chimeric Antigen Receptor T Cells Enhance Antitumor Function by Eliciting an Endogenous Antitumor Response Cancer Cell. 2019 Mar 18;35(3):473-488.e6._x000D_ 4: Sun D, Le Coz C, Bunin N, Romberg N. Hematopoietic Stem Cell Transplantation Successfully Treats CD40LG Duplication J Clin Immunol. 2021 Oct;41(7):1668-1670._x000D_ 5: Aloui C, Sut C, Prigent A, Fagan J, Cognasse F, Granados-Herbepin V, Touraine R, Pozzetto B, Aouni M, Fendri C, Hassine M, Chakroun T, Jemni-Yacoub S, Garraud O, Laradi S. Are polymorphisms of the immunoregulatory factor CD40LG implicated in acute transfusion reactions? Sci Rep. 2014 Nov 28;4:7239._x000D_ 6: Díaz Á, González-Alayón I, Pérez-Torrado V, Suárez-Martins M. CD40-CD154: A perspective from type 2 immunity Semin Immunol. 2021 Mar;53:101528._x000D_ 7: Jobling K, Ng WF. CD40 as a therapeutic target in Sjögren's syndrome Expert Rev Clin Immunol. 2018 Jul;14(7):535-537._x000D_ 8: Lu Q, Wu A, Tesmer L, Ray D, Yousif N, Richardson B. Demethylation of CD40LG on the inactive X in T cells from women with lupus J Immunol. 2007 Nov 1;179(9):6352-8._x000D_ 9: Lutgens E, Daemen MJ. CD40-CD40L interactions in atherosclerosis Trends Cardiovasc Med. 2002 Jan;12(1):27-32._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/31168100">10: Onuora S. Engineered fusion protein disrupts CD40 signalling Nat Rev Rheumatol. 2019 Jul;15(7):385. </a>_x000D_ _x000D_ <strong>Products Related to Human CD40LG Protein can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>