Ac-rC Phosphoramidite-15N3

Ac-rC Phosphoramidite-15N3 is 15N labeled Ac-rC Phosphoramidite (HY-W042357) . Ac-rC Phosphoramidite is used for the oligoribonucleotide phosphorodithioate modification (PS2-RNA) .

Product Specifications

UNSPSC

12352005

Target

DNA/RNA Synthesis; Isotope-Labeled Compounds

Type

Isotope-Labeled Compounds

Related Pathways

Cell Cycle/DNA Damage; Others

Applications

Cancer-programmed cell death

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/ac-rc-phosphoramidite-15n3.html

Solubility

10 mM in DMSO

Smiles

COC(C=C1)=CC=C1C(C2=CC=CC=C2)(C3=CC=C(OC)C=C3)OC[C@@H]4[C@@H](OP(N(C(C)C)C(C)C)OCCC#N)[C@@H](O[Si](C)(C)C(C)(C)C)[C@H]([15N]5C=CC([15NH]C(C)=O)=[15N]C5=O)O4

Molecular Formula

C47H64N2 15N3O9PSi

Molecular Weight

905.08

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]Wipapat Kladwang, et al. Anomalous Reverse Transcription through Chemical Modifications in Polyadenosine Stretches. Biochemistry. 2020 Jun 16;59 (23) :2154-2170.