LAIR1 Recombinant Mouse Monoclonal Antibody [PSH04-50]
Leukocyte-associated immunoglobulin-like receptor 1 is a protein that in humans is encoded by the LAIR1 gene.[5][6] LAIR1 has also been designated as CD305 (cluster of differentiation 305). The protein encoded by this gene is an inhibitory receptor found on peripheral mononuclear cells, including NK cells, T cells, and B cells. Inhibitory receptors regulate the immune response to prevent lysis of cells recognized as self. The gene is a member of both the immunoglobulin superfamily and the leukocyte-associated inhibitory receptor family. The gene maps to a region of 19q13.4 called the leukocyte receptor cluster, which contains at least 29 genes encoding leukocyte-expressed receptors of the immunoglobulin superfamily.
Product Specifications
Product Name Alternative
Abbreviation
LAIR1, CD305
Swiss Prot
Q6GTX8 Human
Cellular Locus
Cell membrane.
Host
Mouse
Species Reactivity
Human
Immunogen
Recombinant protein within human LAIR1 aa 166-287 / 287.
Isotype
IgG1
Clone
PSH04-50
Conjugation
Non-conjugated
Type
Recombinant Mouse monoclonal Antibody
Applications
WB, IHC-P
Positive Control
THP-1 cell lysate, HL-60 cell lysate, human lymph node tissue.
Concentration
1 mg/mL
Dilution
WB: 1:2,000 ;IHC-P: 1:200
Purity
Protein A affinity purified.
Form
Liquid
Buffer
PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 32 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes
CAS Number
9000-83-3
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