LAIR1 Recombinant Mouse Monoclonal Antibody [PSH04-50]
Leukocyte-associated immunoglobulin-like receptor 1 is a protein that in humans is encoded by the LAIR1 gene.[5][6] LAIR1 has also been designated as CD305 (cluster of differentiation 305). The protein encoded by this gene is an inhibitory receptor found on peripheral mononuclear cells, including NK cells, T cells, and B cells. Inhibitory receptors regulate the immune response to prevent lysis of cells recognized as self. The gene is a member of both the immunoglobulin superfamily and the leukocyte-associated inhibitory receptor family. The gene maps to a region of 19q13.4 called the leukocyte receptor cluster, which contains at least 29 genes encoding leukocyte-expressed receptors of the immunoglobulin superfamily.
Product Specifications
CAS Number
9000-83-3
Product Name Alternative
Abbreviation
LAIR1, CD305
Swiss Prot
Q6GTX8 Human
Cellular Locus
Cell membrane.
Host
Mouse
Species Reactivity
Human
Immunogen
Recombinant protein within human LAIR1 aa 166-287 / 287.
Isotype
IgG1
Clone
PSH04-50
Conjugation
Non-conjugated
Type
Recombinant Mouse monoclonal Antibody
Applications
WB, IHC-P
Positive Control
THP-1 cell lysate, HL-60 cell lysate, human lymph node tissue.
Concentration
1 mg/mL
Dilution
WB: 1:2,000 ;IHC-P: 1:200
Purity
Protein A affinity purified.
Form
Liquid
Buffer
PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 32 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes
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