QYL-685
QYL-685 is a Z-methenylcyclopropane nucleoside analog containing 2,6-diaminopurine, which has strong antiviral activity against HIV-1. QYL-685 showed activity against Zidovudine resistant and Didanosine (HY-B0249) resistant HIV-1 infected clones in vitro. QYL-685 can be developed as a therapeutic drug for HIV-1 infection[1].
Product Specifications
CAS Number
210355-14-9
UNSPSC
12352005
Target
HIV
Type
Reference compound
Related Pathways
Anti-infection
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/qyl-685.html
Smiles
C[C@H](NP(OC1=CC=CC=C1)(OCC2/C(C2)=C\N3C=NC4=C(N=C(N=C34)N)N)=O)C(OC)=O
Molecular Formula
C20H24N7O5P
Molecular Weight
473.42
References & Citations
[1]Uchida H, et al. In vitro anti-human immunodeficiency virus activities of Z-and E-methylenecyclopropane nucleoside analogues and their phosphoro-L-alaninate diesters[J]. Antimicrobial agents and chemotherapy, 1999, 43 (6) : 1487-1490.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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