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QYL-685

QYL-685 is a Z-methenylcyclopropane nucleoside analog containing 2,6-diaminopurine, which has strong antiviral activity against HIV-1. QYL-685 showed activity against Zidovudine resistant and Didanosine (HY-B0249) resistant HIV-1 infected clones in vitro. QYL-685 can be developed as a therapeutic drug for HIV-1 infection[1].

Product Specifications

CAS Number

210355-14-9

UNSPSC

12352005

Target

HIV

Type

Reference compound

Related Pathways

Anti-infection

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/qyl-685.html

Smiles

C[C@H](NP(OC1=CC=CC=C1)(OCC2/C(C2)=C\N3C=NC4=C(N=C(N=C34)N)N)=O)C(OC)=O

Molecular Formula

C20H24N7O5P

Molecular Weight

473.42

References & Citations

[1]Uchida H, et al. In vitro anti-human immunodeficiency virus activities of Z-and E-methylenecyclopropane nucleoside analogues and their phosphoro-L-alaninate diesters[J]. Antimicrobial agents and chemotherapy, 1999, 43 (6) : 1487-1490.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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