Squalestatin 3
Squalestatin 3 is a secondary metabolite, which can be isolated from Phoma. Squalestatin 3 is an inhibitor for squalene synthase with an IC50 of 6 nM[1].
Product Specifications
CAS Number
142505-92-8
UNSPSC
12352005
Target
Endogenous Metabolite
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/squalestatin-3.html
Smiles
OC([C@@]12[C@@](O)([C@H](O[C@@]([C@H](O)[C@H]2O)(CCC([C@@H](OC(C)=O)[C@H](C)CC3=CC=CC=C3)=C)O1)C(O)=O)C(O)=O)=O
Molecular Formula
C25H30O13
Molecular Weight
538.50
References & Citations
[1]Watson N S, et al. The squalestatins: potent inhibitors of squalene synthase. The role of the tricarboxylic acid moiety[J]. Bioorganic & Medicinal Chemistry Letters, 1993, 3 (12) : 2541-2546.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Frequently Asked Questions
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