D-Pro-Phe-Arg-pNA (hydrochloride)

D-Pro-Phe-Arg-pNA hydrochloride is the substrate for thrombin-like enzyme, with Km of 50.7 μM[1].

Product Specifications

CAS Number

[62354-56-7]

UNSPSC

12352209

Target

Thrombin

Type

Peptides

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/d-pro-phe-arg-pna-hydrochloride.html

Purity

99.58

Solubility

10 mM in DMSO

Smiles

O=C(NC1=CC=C(C=C1)[N+]([O-])=O)[C@H](CCCNC(N)=N)NC([C@@H](NC([C@H]2CCCN2)=O)CC3=CC=CC=C3)=O.Cl.Cl

Molecular Formula

C26H36Cl2N8O5

Molecular Weight

611.52

References & Citations

[1]Magalhães HP, et al., Mechanism of action and determination of the best substrate for a thrombin-like enzyme from Lachesis muta muta venom by regression analysis of the kinetic parameters determined with peptidyl p-nitroanilide substrates. Toxicon. 2006 Mar 15;47 (4) :453-8.