Eliglustat-d15
Product Specifications
UNSPSC Description
Eliglustat-d15 (Genz 99067-d15) is deuterium labeled Eliglustat. Eliglustat is an specific, potent and orally active glucocerebroside synthase inhibitor with an IC50 of 24 nM[1].
Target Antigen
Isotope-Labeled Compounds; Others
Type
Isotope-Labeled Compounds
Related Pathways
Others
Field of Research
Metabolic Disease;Cancer
Smiles
[2H]C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C(N[C@H](CN1CCCC1)[C@@H](C2=CC=C(OCCO3)C3=C2)O)=O
Molecular Weight
419.64
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.|[2]McEachern KA, et al. A specific and potent inhibitor of glucosylceramide synthase for substrate inhibition therapy ofGaucher disease. Mol Genet Metab. 2007 Jul;91(3):259-68.
Shipping Conditions
Room temperature
Clinical Information
No Development Reported
CAS Number
1628700-80-0
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS7072401-01 0.05 mg (E-Coli)
Recombinant Alcanivorax borkumensis Protein TolB (tolB)
Ask
View Details