N-Desalkylflurazepam-d4
N-Desalkylflurazepam-d4 is a deuterated labeled N-Desalkylflurazepam. N-Desalkylflurazepam (Norfludiazepam) is a long-acting metabolite of benzodiazepine compounds, such as Flurazepam. N-Desalkylflurazepam inhibits L-type voltage-gated calcium channels with IC50 values of 55 μM and 37 μM for Cav1.2 and Cav1.3, respectively[1][2].
Product Specifications
CAS Number
1286430-01-0
UNSPSC
12352005
Target
Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Others
Field of Research
Others
Smiles
ClC(C=C1C(C2=C(C([2H])=C([2H])C([2H])=C2[2H])F)=NC3)=CC=C1NC3=O
Molecular Formula
C15H6D4ClFN2O
Molecular Weight
292.73
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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