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N-Desalkylflurazepam-d4

N-Desalkylflurazepam-d4 is a deuterated labeled N-Desalkylflurazepam. N-Desalkylflurazepam (Norfludiazepam) is a long-acting metabolite of benzodiazepine compounds, such as Flurazepam. N-Desalkylflurazepam inhibits L-type voltage-gated calcium channels with IC50 values of 55 μM and 37 μM for Cav1.2 and Cav1.3, respectively[1][2].

Product Specifications

CAS Number

1286430-01-0

UNSPSC

12352005

Target

Isotope-Labeled Compounds

Type

Isotope-Labeled Compounds

Related Pathways

Others

Field of Research

Others

Smiles

ClC(C=C1C(C2=C(C([2H])=C([2H])C([2H])=C2[2H])F)=NC3)=CC=C1NC3=O

Molecular Formula

C15H6D4ClFN2O

Molecular Weight

292.73

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.

Shipping Conditions

Room temperature

Scientific Category

Isotope-Labeled Compounds

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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