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Arachidonic acid

Arachidonic acid (Immunocytophyt) is a polyunsaturated omega-6 fatty acid and a major constituent of biomembranes. Arachidonic acid also acts as the substrate for various lipid mediators, such as prostaglandins (PGs) . Arachidonic acid improves cognitive response and cardiovascular function[1].

Product Specifications

CAS Number

[506-32-1]

Product Name Alternative

Immunocytophyt

UNSPSC

12352211

Hazard Statement

H315, H319

Target

Endogenous Metabolite

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/Arachidonic_acid.html

Purity

99.75

Solubility

DMSO : 100 mg/mL (ultrasonic) |Ethanol : 100 mg/mL (ultrasonic)

Smiles

CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(O)=O

Molecular Formula

C20H32O2

Molecular Weight

304.47

Precautions

H315, H319

References & Citations

[1]Tateishi N, et al. Dietary supplementation with arachidonic acid increases arachidonic acid content in paw, but does not affect arthritis severity or prostaglandin E2 content in rat adjuvant-induced arthritis model. Lipids Health Dis. 2015 Jan 16;14:3.|[2]DiMartino MJ, et al. The pharmacology of arachidonic acid-induced rat paw edema. Agents Actions. 1987 Aug;21 (3-4) :303-5. |[3]Pompeia C, et al. Arachidonic acid cytotoxicity in leukocytes: implications of oxidative stress and eicosanoid synthesis. Biol Cell. 2002 Sep;94 (4-5) :251-65.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, protect from light, stored under nitrogen)

Scientific Category

Natural Products

Clinical Information

No Development Reported

Isoform

Human Endogenous Metabolite

Citation 01

ACS Pharmacol Transl Sci. 2025 Oct 4.|Acta Pharmacol Sin. 2025 Jun 23.|Ann Rheum Dis. 2025 Oct 28:S0003-4967 (25) 04428-0.|Biochem Pharmacol. 2024 Dec;230 (Pt 1) :116574.|Biomed Pharmacother. 2023 Nov:167:115531.|bioRxiv. 2024 May 19.|bioRxiv. 2024 November 26.|bioRxiv. 2025 Jun 16.|Cell Death Differ. 2025 Nov 27.|Cell Death Dis. 2020 Sep 15;11 (9) :756.|Cell Death Dis. 2023 Jun 13;14 (6) :359.|Cell Mol Gastroenterol Hepatol. 2022;13 (6) :1805-1827.|Cell Rep. 2022 Sep 20;40 (12) :111381.|Cell Rep. 2024 Jul 9;43 (7) :114477.|Cell Rep. 2025 Apr 16;44 (5) :115572.|Cell Rep. 2025 Nov 25;44 (11) :116496.|Clin Exp Pharmacol Physiol. 2024 Oct;51 (10) :e13918.|Clin Nutr. 2023 Dec 30;43 (2) :453-467.|Dev Cell. 2025 Apr 18:S1534-5807 (25) 00206-0.|Eur J Pharmacol. 2023 Apr 15:945:175618.|FASEB J. 2024 Dec 15;38 (23) :e70226.|Food Funct. 2024 Sep 30;15 (19) :9916-9927.|Free Radic Biol Med. 2023 Jun:202:110-120.|Front Pharmacol. 2022 Jan 10;12:792263.|Gut Microbes. 2023 Dec;15 (2) :2265578.|Immunity. 2024 Aug 22:S1074-7613 (24) 00376-5.|Int Immunopharmacol. 2024 Oct 7;143 (Pt 1) :113320.|Int J Parasitol Drugs Drug Resist. 2024 Jun 6:25:100551.|J Anal Test. 2024 Dec.|J Biol Chem. 2022 May;298 (5) :101847.|J Biol Chem. 2024 Apr;300 (4) :107168.|J Ethnopharmacol. 2026 Feb 28:357:120892.|J Sep Sci. 2025 Nov;48 (11) :e70312.|Nat Cancer. 2025 May;6 (5) :768-785.|Nat Commun. 2024 Sep 10;15 (1) :7914.|Nat Commun. 2025 Jun 5;16 (1) :5209.|Nat Commun. 2025 Sep 29;16 (1) :8541.|Nature. 2025 Jul;643 (8070) :192-200.|Phytomedicine. 2025 Oct 25:148:157450.|Redox Biol. 2021 Nov:47:102168.|Redox Biol. 2023 Oct:66:102857.|Redox Biol. 2025 Feb 3:80:103528.|Rev Bras Farmacogn. 2023 May 20.|Science. 2025 Mar 14;387 (6739) :eadm9805.|Signal Transduct Target Ther. 2024 Dec 30;9 (1) :367.|SSRN. 2024 Sep 20.|Thromb J. 2025 May 7;23 (1) :44.|Xenobiotica. 2022 Jul;52 (7) :669-675.|Nat Nanotechnol. 2025 Oct 31.

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