Sulconazole

Sulconazole is a potent antifungal agent in the imidazole class. Sulconazole blocks the NF-κB/IL-8 signaling pathway and CSC (Cancer stem cells) formation. Sulconazole inhibits tumor growth, and can be used for breast cancer research[1].

Product Specifications

CAS Number

[61318-90-9]

Product Name Alternative

(±) -Sulconazole

UNSPSC

12352005

Hazard Statement

H302-H315-H319

Target

Fungal

Type

Reference compound

Related Pathways

Anti-infection

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/sulconazole.html

Solubility

10 mM in DMSO

Smiles

ClC1=CC=C(C(SCC2=CC=C(Cl)C=C2)CN3C=CN=C3)C(Cl)=C1

Molecular Formula

C18H15Cl3N2S

Molecular Weight

397.75

Precautions

P264-P270-P280-P302+P352-P305+P351+P338-P330-P362+P364-P501

References & Citations

[1]Choi HS, et al. Disruption of the NF-κB/IL-8 Signaling Axis by Sulconazole Inhibits Human Breast Cancer Stem Cell Formation. Cells. 2019;8 (9) :1007.