What is the catalog number for PIK-93?

The catalog number for PIK-93 is HY-12046.

What sizes are available for PIK-93?

PIK-93 is available in the following size(s): 1 mg, 5 mg, 10 mM - 1 mL, 10 mg, 50 mg, 100 mg.

How many pack sizes does PIK-93 come in?

PIK-93 is available in 6 different pack sizes.

PIK-93 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures PIK-93?

PIK-93 is manufactured by QuantiMol.

What is the estimated delivery time for PIK-93?

Estimated delivery time for PIK-93 is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for PIK-93?

The safety data sheet for PIK-93 is available here: http://file.medchemexpress.com/batch_PDF/HY-12046/PIK-93-SDS-MedChemExpress.pdf.

PIK-93

PIK-93 is the first potent, synthetic PI4K (PI4KIIIβ) inhibitor with IC50 of 19 nM, and also inhibits PI3Kγ and PI3Kα with IC50 of 16 nM and 39 nM, respectively.

Product Specifications

CAS Number

593960-11-3

UNSPSC

12352005

Hazard Statement

H317, H319

Target

PI3K; PI4K; Virus Protease

Type

Reference compound

Related Pathways

Anti-infection; PI3K/Akt/mTOR

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/PIK-93.html

Purity

99.81

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

CC(NC1=NC(C)=C(S1)C2=CC=C(C(S(=O)(NCCO)=O)=C2)Cl)=O

Molecular Formula

C14H16ClN3O4S2

Molecular Weight

389.88

Precautions

H317, H319

References & Citations

[1]Knight ZA, et al. A pharmacological map of the PI3-K family defines a role for p110alpha in insulin signaling. Cell. 2006 May 19;125 (4) :733-47|[2]Van Keymeulen A, et al. To stabilize neutrophil polarity, PIP3 and Cdc42 augment RhoA activity at the back as well as signals at the front. J Cell Biol. 2006 Jul 31;174 (3) :437-45|[3]Toth B, et al. Phosphatidylinositol 4-kinase IIIbeta regulates the transport of ceramide between the endoplasmic reticulum and Golgi. J Biol Chem. 2006 Nov 24;281 (47) :36369-77|[4]Monet M, et al. Involvement of phosphoinositide 3-kinase and PTEN protein in mechanism of activation of TRPC6 protein in vascular smooth muscle cells. J Biol Chem. 2012 May 18;287 (21) :17672-81|[5]Arita M, et al. Phosphatidylinositol 4-kinase III beta is a target of enviroxime-like compounds for antipoliovirus activity. J Virol. 2011 Mar;85 (5) :2364-72