MB-0223
MB-0223 is a potent and selective dynamin-related GTPase Drp1 partial inhibitor (IC50=1.3 μM) over other dynamin family members, Opa 1 and dynamin-1 (IC50>100 μM) [1].
Product Specifications
CAS Number
2247732-89-2
UNSPSC
12352005
Target
Dynamin
Type
Reference compound
Related Pathways
Cytoskeleton
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mb-0223.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC(C)=CN1CC2=CSC(N3CCCCC3)=N2)NC4=CC=C(C5=CC=CN=C5)C=C4
Molecular Formula
C26H27N5OS
Molecular Weight
457.59
References & Citations
[1]Ashley Mallat, et al. Characterization of Small Molecule Inhibitors of Drp1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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