Satavaptan
Satavaptan (SR 121463) is an antagonist for vasopressin V2 receptor. Satavaptan regulates the vasopressin regulated phosphopeptides and vasopressin-mediated signaling pathway. Satavaptan is potential in ameliorating hyponatremia[1].
Product Specifications
CAS Number
185913-78-4
Product Name Alternative
SR 121463
UNSPSC
12352005
Hazard Statement
H302-H361
Target
Vasopressin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/satavaptan.html
Smiles
O=C(NC(C)(C)C)C1=CC=C(S(=O)(N2C([C@@]3(C4=C2C=CC(OCC)=C4)CC[C@H](OCCN5CCOCC5)CC3)=O)=O)C(OC)=C1
Molecular Formula
C33H45N3O8S
Molecular Weight
643.79
Precautions
P264-P270-P280-P330-P405-P501
References & Citations
[1]Hoffert JD, et al., Global analysis of the effects of the V2 receptor antagonist satavaptan on protein phosphorylation in collecting duct. Am J Physiol Renal Physiol. 2014 Feb 15;306 (4) :410-21.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 3
Frequently Asked Questions
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