Satavaptan

Satavaptan (SR 121463) is an antagonist for vasopressin V2 receptor. Satavaptan regulates the vasopressin regulated phosphopeptides and vasopressin-mediated signaling pathway. Satavaptan is potential in ameliorating hyponatremia[1].

Product Specifications

CAS Number

[185913-78-4]

Product Name Alternative

SR 121463

UNSPSC

12352005

Hazard Statement

H302-H361

Target

Vasopressin Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/satavaptan.html

Smiles

O=C(NC(C)(C)C)C1=CC=C(S(=O)(N2C([C@@]3(C4=C2C=CC(OCC)=C4)CC[C@H](OCCN5CCOCC5)CC3)=O)=O)C(OC)=C1

Molecular Formula

C33H45N3O8S

Molecular Weight

643.79

Precautions

P264-P270-P280-P330-P405-P501

References & Citations

[1]Hoffert JD, et al., Global analysis of the effects of the V2 receptor antagonist satavaptan on protein phosphorylation in collecting duct. Am J Physiol Renal Physiol. 2014 Feb 15;306 (4) :410-21.