Salicylic acid-13C6

Salicylic acid-13C6 is the 13C-labeled Salicylic acid (HY-B0167) . Salicylic acid is a precursor to and a metabolite of Aspirin (HY-14654), can inhibit cyclo-oxygenase-2 (COX-2) activity[1][2].

Product Specifications

CAS Number

[1189678-81-6]

Product Name Alternative

2-Hydroxybenzoic acid-13C6

UNSPSC

12352005

Hazard Statement

H302, H318

Target

Apoptosis; Autophagy; COX; Endogenous Metabolite; Isotope-Labeled Compounds; Mitophagy

Type

Isotope-Labeled Compounds

Related Pathways

Apoptosis; Autophagy; Immunology/Inflammation; Metabolic Enzyme/Protease; Others

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology; Cancer

Assay Protocol

https://www.medchemexpress.com/salicylic-acid-13c6.html

Purity

97.0

Solubility

10 mM in DMSO|DMSO : ≥ 50mg/mL|H2O : 1mg/mL (ultrasonic)

Smiles

OC([13C]1=[13C]([13CH]=[13CH][13CH]=[13CH]1)O)=O

Molecular Formula

C 13C6H6O3

Molecular Weight

144.08

Precautions

H302, H318

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]Mitchell JA, et al. Sodium salicylate inhibits cyclo-oxygenase-2 activity independently of transcription factor (nuclear factor kappaB) activation: role of arachidonic acid. Mol Pharmacol. 1997 Jun;51 (6) :907-12.; Nixon M, et al. Salicylate downregulates 11