Histone H2A.Z (Acetyl Lys7) rabbit pAb
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent member of the histone H2A family that is distinct from other members of the family. Studies in mice have shown that this particular histone is required for embryonic development and indicate that lack of functional histone H2A leads to embryonic lethality. [provided by RefSeq, Jul 2008],
Product Specifications
Background
Synonyms
H2AFZ; H2AZ; Histone H2A.Z; H2A/z
Gene ID
3015
UniProt
P0C0S5
Cellular Locus
Nucleus. Chromosome.
Host
Rabbit
Species Reactivity
Human,Mouse,Rat
Reactivity
Human; Mouse; Rat
Immunogen
Synthetic Peptide of Histone H2A.Z (Acetyl Lys7)
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB
Validated Applications
WB
Stability
-20°C/1 year
Dilution
WB: 1:500-1000
Molecular Weight
14kD
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES20532-1.pdf
Observed Molecular Weight
14 kD
Subcellular Location
Nucleus. Chromosome.
Other Product Names
H2AFZ; H2AZ; Histone H2A.Z; H2A/z
Gene ID (Human)
3015
SwissProt (Human)
P0C0S5
Available Sizes
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