ACT-373898
Product Specifications
UNSPSC Description
ACT-373898 is an inactive carboxylic acid metabolite of Macitentan. Macitentan is an orally active, non-peptide dual ETA and ETB (endothelin receptor) antagonist[1].
Target Antigen
Endothelin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Field of Research
Endocrinology
Assay Protocol
https://www.medchemexpress.com/act-373898.html
Smiles
O=C(O)COC1=NC=NC(NS(=O)(NCCC)=O)=C1C2=CC=C(Br)C=C2
Molecular Weight
445.29
References & Citations
[1]Shirin Bruderer, et al. Effect of cyclosporine and rifampin on the pharmacokinetics of macitentan, a tissue-targeting dual endothelin receptor antagonist. AAPS J. 2012 Mar;14(1):68-78.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-135500/ACT-373898-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-135500/
CAS Number
1433875-14-9
Available Sizes
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