TMB Free Base

<strong>TMB Free Base</strong>_x000D_ <strong>Catalog number:</strong> B2016281_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 5 g_x000D_ <strong>Molecular Weight or Concentration:</strong> 240.35 g/mol_x000D_ <strong>Supplied as:</strong> Powder_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> 2-8°C_x000D_ <strong>Keywords:</strong> 3,3’,5,5’-Tetramethylbenzidine, free base_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Jiang M, Jia K, Wang L, Li W, Chen B, Liu Y, Wang H, Zhao S, He Y, Zhou C. Alterations of DNA damage response pathway: Biomarker and therapeutic strategy for cancer immunotherapy Acta Pharm Sin B. 2021 Oct;11(10):2983-2994. TMB_x000D_ 2: León-Castillo A, Britton H, McConechy MK, McAlpine JN, Nout R, Kommoss S, Brucker SY, Carlson JW, Epstein E, Rau TT, Bosse T, Church DN, Gilks CB. Interpretation of somatic POLE mutations in endometrial carcinoma J Pathol. 2020 Mar;250(3):323-335._x000D_ 3: Fulton-Ward T, Middleton G. The impact of genomic context on outcomes of solid cancer patients treated with genotype-matched targeted therapies: a comprehensive review Ann Oncol. 2023 Dec;34(12):1113-1130. TMB_x000D_ 4: Sun R, Li Z, Bishop TC. TMB Library of Nucleosome Simulations J Chem Inf Model. 2019 Oct 28;59(10):4289-4299. TMB_x000D_ 5: Nutiu R, Li Y. Tripartite molecular beacons Nucleic Acids Res. 2002 Sep 15;30(18):e94._x000D_ 6: Moog S, Lamartina L, Bani MA, Al Ghuzlan A, Friboulet L, Italiano A, Lacroix L, Postel Vinay S, Tselikas L, Deschamps F, Bonnet B, Pani F, Baudin E, Hadoux J. Alkylating Agent-Induced High Tumor Mutational Burden in Medullary Thyroid Cancer and Response to Immune Checkpoint Inhibitors: Two Case Reports Thyroid. 2023 Nov;33(11):1368-1373._x000D_ 7: Feng D, Wang J, Shi X, Li D, Wei W, Han P. Membrane tension-mediated stiff and soft tumor subtypes closely associated with prognosis for prostate cancer patients Eur J Med Res. 2023 May 13;28(1):172._x000D_ 8: Pai SG, Carneiro BA, Chae YK, Costa RL, Kalyan A, Shah HA, Helenowski I, Rademaker AW, Mahalingam D, Giles FJ. Correlation of tumor mutational burden and treatment outcomes in patients with colorectal cancer J Gastrointest Oncol. 2017 Oct;8(5):858-866._x000D_ 9: Yan H, Song L, Li Y, Xu Q, Guo W, Lin S, Jiang W, Wang Z, Deng L, Huang Z, Qin H, Zhang X, Tong F, Zhang R, Liu Z, Zhang L, Yu J, Dong X, Gong Q, Deng J, Chen X, Wang J, Zhang G, Yang N, Zhang Y, Zeng L. Clinical evidence for efficacy of pembrolizumab in MSI-H and TMB-H advanced solid tumor: results from three cancer centers in China Cancer Immunol Immunother. 2024 Mar 7;73(4):74._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/33255068">10: Lin C, Du Y, Wang S, Wang L, Song Y. Glucose oxidase@Cu-hemin metal-organic framework for colorimetric analysis of glucose Mater Sci Eng C Mater Biol Appl. 2021 Jan;118:111511. </a>_x000D_ _x000D_ <strong>Products Related to TMB Free Base can be found at</strong> <a href="https://moleculardepot.com/product-category/Substrates/"> Substrates</a>