Ro 31-0052
Ro 31-0052 is a basic radiation sensitizer, a 3'-hydroxypiperidine analog of Ro 03-8799, with improved hydrophilicity. This type of designed radiation sensitizer has better pharmacokinetic properties and has the potential to replace clinically used Misonidazole and Metronidazole (HY-B0318).
Product Specifications
CAS Number
82381-67-7
UNSPSC
12352005
Target
Biochemical Assay Reagents
Type
Reference compound
Related Pathways
Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/ro-31-0052.html
Smiles
OC(CN1CC(CCC1)O)CN2C=CN=C2[N+]([O-])=O
Molecular Formula
C11H18N4O4
Molecular Weight
270.29
References & Citations
[1]Dennis MF, Stratford MR, Wardman P, Watts ME. Cellular uptake of misonidazole and analogues with acidic or basic functions. Int J Radiat Biol Relat Stud Phys Chem Med. 1985 Jun;47 (6) :629-43.|[2]Stratford M R L, et al. Pharmacokinetic studies on some novel (2-nitro-1-imidazolyl) propanolamine radiosensitizers[J]. Advanced Topics on Radiosensitizers of Hypoxic Cells, 1982: 165-169.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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