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COX-2-IN-49

COX-2-IN-49 (compound 6c) is a potent cyclooxygenase-2 (COX-2) inhibitor with an IC50 value of 2.671 µM. COX-2-IN-49 shows antiproliferative activity. COX-2-IN-49 has the potential for the research of cancer[1].

Product Specifications

UNSPSC

12352005

Target

COX

Type

Reference compound

Related Pathways

Immunology/Inflammation

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/cox-2-in-49.html

Smiles

CC(C1=CC=C(CC(C)C)C=C1)C(N/N=C(C(C2=O)=CC3=C(O2)C(Br)=CC(Br)=C3)\C)=O

Molecular Formula

C24H24Br2N2O3

Molecular Weight

548.27

References & Citations

[1]Wu F, et al. AILDE Computer-Aided Discovery of Novel Ibuprofen-Coumarin Antitumor Lead Compounds Targeting Cyclooxygenase-2. ACS Omega. 2024 Sep 19;9 (39) :41021-41031.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

COX-2

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