COX-2-IN-49
COX-2-IN-49 (compound 6c) is a potent cyclooxygenase-2 (COX-2) inhibitor with an IC50 value of 2.671 µM. COX-2-IN-49 shows antiproliferative activity. COX-2-IN-49 has the potential for the research of cancer[1].
Product Specifications
UNSPSC
12352005
Target
COX
Type
Reference compound
Related Pathways
Immunology/Inflammation
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cox-2-in-49.html
Smiles
CC(C1=CC=C(CC(C)C)C=C1)C(N/N=C(C(C2=O)=CC3=C(O2)C(Br)=CC(Br)=C3)\C)=O
Molecular Formula
C24H24Br2N2O3
Molecular Weight
548.27
References & Citations
[1]Wu F, et al. AILDE Computer-Aided Discovery of Novel Ibuprofen-Coumarin Antitumor Lead Compounds Targeting Cyclooxygenase-2. ACS Omega. 2024 Sep 19;9 (39) :41021-41031.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
COX-2
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC471429-100 1x 100 µL
E-Cadherin / CD324 (Intercellular Junction Marker) (4A2), CF647 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC941429-500 1x 500 µL
E-Cadherin / CD324 (Intercellular Junction Marker) (4A2), CF594 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC400806-100 1x 100 µL
TYRP1 (Tyrosinase Related Protein 1) (TA99), CF640R conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC400745-500 1x 500 µL
CD45 / LCA (2B11 + PD7/26), CF640R conjugate, 0.1mg/mL
Sign In for Pricing
View Details