HIF-2α-IN-16

HIF-2α-IN-16 (48) is a HIF-2α inhibitor, with an IC50 of 0.091 μM[1].

Product Specifications

CAS Number

[3033981-97-1]

UNSPSC

12352005

Target

HIF/HIF Prolyl-Hydroxylase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/hif-2α-in-16.html

Smiles

O=C(C1=CC=C(F)C(C(F)F)=N1)N2[C@@]3(CCC(F)(C3)F)[C@@H](C(F)(C2)F)O

Molecular Formula

C15H13F7N2O2

Molecular Weight

386.26

References & Citations

[1]Zhiguo Liu, et al. Pyridinylamide derivative, pharmaceutical composition comprising same, and medical use thereof. Patent. WO2024067709A1.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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