ODN 2336 (sodium)
ODN 2336 sodium is a A-Class CpG ODN (oligodeoxynucleotides), is a potent TLR9 agonist. ODN 2336 sodium induces the production of IFN-α. ODN 2336 sodium up-regulates the expression of IP-10 mRNA and IL-18 mRNA. ODN 2336 sodium can be used as adjuvant of vaccines[1][2][3].
Product Specifications
UNSPSC
12352208
Target
Toll-like Receptor (TLR)
Type
Oligonucleotides
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/odn-2336-sodium.html
Purity
97.80
Solubility
10 mM in H2O
Smiles
[ODN2336(sodium)]
Molecular Weight
6761.7 (free acid)
References & Citations
[1]urk M, et al. C-Class CpG ODN: sequence requirements and characterization of immunostimulatory activities on mRNA level. Immunobiology. 2004;209 (1-2) :141-54. |[2]old MC, et al. Purified neonatal plasmacytoid dendritic cells overcome intrinsic maturation defect with TLR agonist stimulation. Pediatr Res. 2006 Jul;60 (1) :34-7.|[3]Hilbert T, et al. Beta2-adrenoceptor stimulation suppresses TLR9-dependent IFNA1 secretion in human peripheral blood mononuclear cells. PLoS One. 2013 May 28;8 (5) :e65024.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Oligonucleotides
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC881045-100 1x 100 µL
CD16 (C16/1045), CF488A conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC880096-100 1x 100 µL
Histone H1 (AE-4), CF488A conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC940413-100 1x 100 µL
Chromogranin A (CHGA/413), CF594 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC940940-100 1x 100 µL
Glucose Regulated Protein 94 (GRP94) (9G10.F8.2), CF594 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC940218-500 1x 500 µL
CD100 (Semaphorin-4D) (A8), CF594 conjugate, 0.1mg/mL
Sign In for Pricing
View Details