Dalfopristin

Dalfopristin (RP54476) is a semisynthetic sulfone antibiotic. Dalfopristin alone has limited antibacterial activity, but synergistically with Quinupristin it has significant bactericidal activity against many pathogenic Gram-positive cocci[1].

Product Specifications

CAS Number

[112362-50-2]

Product Name Alternative

RP54476

UNSPSC

12352005

Hazard Statement

H315, H319, H320

Target

Antibiotic; Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/Dalfopristin.html

Concentration

10mM

Purity

99.67

Solubility

DMSO : ≥ 100 mg/mL

Smiles

O=S(CCN(CC)CC)([C@H]1[C@@](C(O[C@H]([C@@H](/C=C/C(NC/C=C\C(C)=C\2)=O)C)C(C)C)=O)([H])N(C(C3=COC(CC(C[C@@H]2O)=O)=N3)=O)CC1)=O

Molecular Formula

C34H50N4O9S

Molecular Weight

690.85

Precautions

H315, H319, H320

References & Citations

[1]A Le Liboux, et al. Simultaneous high-performance liquid chromatographic determination of quinupristin, dalfopristin and their main metabolites in human plasma. J Chromatogr B Biomed Sci Appl. 1998 Apr 24;708 (1-2) :161-8. |[2]Martinet MR, et al. Lack of effect of streptogramins on hepatic drug metabolism enzymes in the rat. Drug Metab Dispos. 1992 Jul-Aug;20 (4) :490-5.