CARM1-IN-3 (dihydrochloride)
Product Specifications
UNSPSC Description
CARM1-IN-3 dihydrochloride (compound 17b) is a potent and selective co-activator associated arginine methyltransferase (CARM1) inhibitor with IC50 values of 0.07, >25 µM for CARM1 and CARM3, respectively[1].
Target Antigen
Histone Methyltransferase
Type
Reference compound
Related Pathways
Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/carm1-in-3-dihydrochloride.html
Solubility
DMSO : 50 mg/mL (ultrasonic)|H2O : 50 mg/mL (ultrasonic)
Smiles
CNCCN1CCC(C2=CC3=C(N=C(C4=C(OC)C=CC=C4OC)N3)C(C)=C2)CC1.Cl.Cl
Molecular Weight
481.46
References & Citations
[1]Wan H, et al. Benzo[d]imidazole inhibitors of Coactivator Associated Arginine Methyltransferase 1 (CARM1)--Hit to Lead studies. Bioorg Med Chem Lett. 2009 Sep 1;19(17):5063-6.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-15214A/CARM1-IN-3-dihydrochloride-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-15214A/CARM1-IN-3-dihydrochloride-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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